Nature Reviews Drug Discovery, Sep. 2014

'Administering biopharmaceuticals' by Susanne Harris, inspired by the Review entitled "Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies"; Nature Reviews Drug Discovery 13, 655–672 (2014).

Nano Letters, Jan. 2014

The cover depicts a microfluidic device that removes bacteria from the blood of a septic patient by use of synthetic ligand-coated magnetic nanoparticles (MNPs). MNPs that rapidly bind to bacteria are removed from the blood stream by the external magnet, and the purified blood is returned to the patient. This process can achieve near-complete removal of both Gram-positive and Gram-negative bacteria from the bloodstream at high flow rates in septic patients.

Advanced Materials, Aug. 2013

Nature Biotechnology, July 2013

The findings offer the first evidence that this gene-editing technique, known as CRISPR, can reverse disease symptoms in living animals. CRISPR, which offers an easy way to snip out mutated DNA and replace it with the correct sequence, holds potential for treating many genetic disorders.

JACS, May 2012

Drug-carrying nanoparticles that shrink and release their payload when irradiated with UV light could offer a way to get drugs deep into tissues and unleash them on demand. This could be a valuable therapeutic tool for diseases such as cancer.

Advanced Materials, Sept. 2009

Scanning electron micrograph of an accordion-like honeycomb scaffold for myocardial tissue engineering that was explicitly designed to match the structural and mechanical properties of native heart. Citation: Freed, L.E., Engelmayr, G.C., Borenstein, J.T., Moutos, F.T., Guilak, F. Advanced Material Strategies for Tissue Engineering Scaffolds. Advanced Materials, 21 (32-33): 3410-3418, 2009.

Nature Materials, Dec. 2008

Confocal micrograph of an accordion-like honeycomb scaffold with cultured rat heart cells (scaffold is colored blue; seeded, living heart cells are colored green with blue nuclei). Citation: Engelmayr, G.C., Cheng, M., Bettinger, C.J., Borenstein, J.T., Langer, R., Freed, L.E. Accordion-Like Honeycombs for Tissue Engineering of Cardiac Anisotropy. Nature Materials,7: 1003-1010, 2008.